Abstract Immunotherapies are revolutionizing cancer care, but many patients do not achieve durable responses and immune-related adverse events are difficult to predict.Quantifying the hundreds of proteins involved in cancer immunity has the potential to provide biomarkers to monitor and predict tumor response.We previously developed robust, multipl
A New Design Method for Industrial Portal Frames in Fire
Industrial portal frames near to other buildings must keep their vertical walls standing in fire in order to prevent fire spread.A recently developed analysis, implemented in the program Vulcan, using a combination of static and dynamic Mens Bags solvers, has shown that the strong base connections recommended by the current design method may not al
The Performance Assessment of a Semisubmersible Platform Subjected to Wind and Waves by a CFD/6-DOF Approach
The semisubmersible platform is one of the Truck Model Kit most important equipment for the exploitation of deep-sea oil and gas.And its survival and operational capacities depend on the towing and motion performances.The present work investigates the properties of different platform component designs based on their towing and motion performances u
Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss
The outcome of cochlear implantation depends on multiple variables including the underlying health of the cochlea.Brain derived neurotrophic factor (BDNF) has been shown to support spiral ganglion neurons and to improve implant function in animal models.Whether endogenous BDNF or BDNF-regulated proteins can be used as biomarkers to predict cochlear
Forest restoration in a fog oasis: evidence indicates need for cultural awareness in constructing the reference.
BackgroundIn the Peruvian Coastal Desert, an archipelago of fog oases, locally called lomas, are centers of biodiversity and of past human activity.Fog interception by a tree canopy, dominated by the legume tree tara (Caesalpinia spinosa), enables the occurrence Jackets in the Atiquipa lomas (southern Peru) of an environmental island with a diverse